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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000117"/>
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    <!-- http://purl.obolibrary.org/obo/BCGO_0000002 -->

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        <rdfs:label xml:lang="en">mouse strain</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/BCGO_9004556 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/BCGO_9004556">
        <rdfs:label xml:lang="en">Nkx2.2{T2A.cCreGgu} mouse strain</rdfs:label>
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        <ns2:IAO_0000115 xml:lang="en">A mouse strain in which part or all of the targeted gene,  NK2 transcription factor related, locus 2  (NCBI Gene ID: 18088) is replaced to create Nkx2.2{T2A.cCre} using the Loxed Cassette Acceptor allele Nkx2.2{tm1(LCA)}). In this line, one of the two bi-partite Cre molecules, cCre, is placed downstream of Nkx2.2 coding sequence fused with 2a peptide using RMCE in the Nkx2.2[LCA] allele. The presence of the T2A sequence allows for transcription of Nkx2.2 and cCre from the native Nkx2.2 locus at the same time. This mouse line allows the labeling of pancreatic epithelium cells that co-express high levels of Ngn3 and Nkx2.2 during mouse embryonic development.</ns2:IAO_0000115>
        <ns2:IAO_0000118 xml:lang="en">Nkx2.2{T2A.cCreGgu}</ns2:IAO_0000118>
        <ns2:IAO_0000117 xml:lang="en">Person: Mark A. Magnuson, Jill Lindner, Jean-Philippe Cartailler</ns2:IAO_0000117>
        <ns2:IAO_0000119 xml:lang="en">Vanderbilt University Medical Center</ns2:IAO_0000119>
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