has part realizes is about has_specified_input has_specified_output achieves_planned_objective inheres in has participant has role deoxyribonucleic acid hydrogensulfite regulation of DNA methylation measurement datum evaluant role reagent role DNA sequencing bisulfite sequencing 8/19/09: Chris says that there may used to be a way of doing bisulfite sequencing comparing lengths of restriction fragments, which implies that it is possible to do without DNA sequencing. An assay which allows to determine the methylation status of genomic DNA using DNA sequencing techniques preceded by a bisulfite based chemical modification of genomic DNA at CpG island location. PMID: 19581485. High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing. Hodges E, Smith A, Kendall J, Xuan Z, Ravi K, Rooks M, Zhang M, Ye K, Battacharjee A, Brizuela L, McCombie WR, Wigler M, Hannon GJ, Hicks J. Genome Res. 2009 Jul 6. Philippe Rocca-Serra adapted from Wikipedia bisulfite sequencing DNA residue methylation epigenetic modification identification objective DNA methylation profiling by high throughput sequencing assay DNA sequence data DNA sequencer metadata complete