process pathogenesis Shane Babcock John Beverley Process that generates the ability of a pathogen to induce disorder in an organism. Process that is the realization of a pathogenic disposition inhering in an pathogen or pathogen population, which in the most common case has at least all of the following proper process parts: (1) pathogen transmission, (2) establishment of localization in host, (3) process of establishing an infection, and (4) appearance of disorder. Pathogenesis does not involve all of (1)-(4) in every case. For instance, in the case of various bacterial pathogens, pathogenesis occurs without (1)-(3) via the secretion of toxins which subsequently cause disorder in some organism. http://purl.obolibrary.org/obo/go.owl