isBiomarkerOfAging disease biological feature ELOVL2 hypermethilation ELOVL2 hypermethylation refers to an increase in DNA methylation at the ELOVL2 gene, which has been consistently associated with aging. The ELOVL2 gene encodes an enzyme involved in the elongation of very long-chain fatty acids. It has emerged as one of the most reliable epigenetic biomarkers of aging. generated with ChatGPT version 4,0 on 19․08․24