kidney disease nephrotic syndrome true MedDRA:10029164 OMIM:618178 OMIM:617783 OMIM:618177 nephrotic syndromes OMIM:618594 DOID:1184 OMIM:618176 OMIM:615861 ICD10:N04 NCIt:C34845 Orphanet:564127 EFO:0004255 A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction. NCIT:C34845 SCTID:52254009 nephrotic syndrome nephrosis ICD9:581.9 nephrotic syndrome (acquired) MeSH:D009404 UMLS:C0027726 syndromes, nephrotic ICD9:581 syndrome, nephrotic MONDO:0005377 A collection of symptoms that include severe edema, proteinuria, and hypoalbuminemia; it is indicative of renal dysfunction. SNOMEDCT:52254009 MESH:D009404 Dani Welter