acute lymphoblastic leukemia cell pre-B acute lymphoblastic leukemia cell BTO:0001094 BrendaTissueOBO The most common subtype, consisting of small uniform lymphoblasts that do not synthesize complete functional immunoglobulins. The term has sometimes been restricted to the minority of the larger group that synthesize heavy chains of immunoglobulins. acute lymphoblastic leukemia cell, pre-B-cell type pre-B leukemia cell