derives from/develops from sarcoma cell smooth muscle leiomyosarcoma cell A malignant tumor cell of smooth muscle origin. Smooth muscle is the major structural component of most hollow internal organs and the walls of blood vessels. Can occur almost anywhere in the body but is most frequent in the uterus and gastrointestinal tract. Complete surgical excision, if possible, is the treatment of choice. BTO:0001631 BrendaTissueOBO