derives from/develops from MDA-MB-435 cell MDA-MB-435S cell BTO:0003941 BrendaTissueOBO MDA-MB-435 S cell MDA-MB-435-S cell This cell line was originally described as a spindle shaped variant of the parental MDA-MB-435 strain isolated from the pleural effusion of a 31 year old female with metastatic, ductal adenocarcinoma of the breast. However, recent studies have reported that this line is cross-contaminated with is the M14 melanoma line.