part of enamel organ stratum intermedium 2011-03-01T09:37:50Z BTO:0005009 BrendaTissueOBO The stratum intermedium in a developing tooth is a layer of two or three cells between the inner enamel epithelium and the newly forming cells of the stellate reticulum. This layer, along with the inner enamel epithelium, is responsible for the tooth enamel formation. It is a part of the dental (enamel) organ. XPMUser