derives from/develops from NCI-H1299 cell H273 cell 2011-05-13T04:34:31Z BTO:0005140 BrendaTissueOBO H1299 cells were transfected with pCMV-p53H273 plasmid. The H273 differs from the wild-type p53 by an arginine to histidine conversion at nucleotides 273. Clones were selected in the presence of G418 for 4 weeks and screened for p53 expression. Mutant p53 H273 has been reported to have strong transactivating activity. XPMUser