derives from/develops from HT-1080 cell 2fTGH cell 2-fTGH cell 2015-09-28T08:33:02Z BTO:0005765 BrendaTissueOBO Marion The human sarcoma cell line HT 1080 was transfected with a vector encoding the selectable marker guanine phosphoribosyltransferase regulated by alpha interferon to create the 2fTGH cell line, enabling the selection of mutations in genes encoding components of the interferon signalling pathway.