human_reference_atlas has characterizing marker set has marker component AIF1 cell cell type (from CL) glial cell microglial cell A central nervous system macrophage found in the parenchyma of the central nervous system. Marker include CD11b-positive, F4/80-positive, and CD68-positive. CT microglia FMA:54539 BTO:0000078 MF.microglia.CNS microglial cell Microglia Unlike macroglial cells, microglial cells arise from hematopoietic stem cells in the yolk sac during early embryogenesis that populate the central nervous system. They derive from embryonic mesoderm and are not from neuroectoderm where glioblast develops from. Markers: Mouse: CD11b+, F4/80+, CD68+. They represent ~12% of the cells in the CNS, but they are not uniformly distributed within the CNS. A normal adult mouse brain has approximately 3.5x10e6 microglia. Microglia are also reportedly CD3-negative, CD4-positive, CD8-negative, CD11b-positive, CD11c-high, CD14-negative, CD19-negative, CD45-low, CD56-negative, CD163-negative, CD200R-positive, CD281-positive, CD282-positive, CD283-positive, CD284-positive, CD285-positive, CD286-positive, CD287-positive, CD288-positive, CD289-positive, Gr1-negative, nestin-positive, and PU.1-positive. hortega cells CL:0000129 brain-resident macrophage microglia BTO:0000962 brain macrophage microglia microglial cell microgliocyte FMA:54540 neuron myeloid leukocyte Homo sapiens sequence collection brain cerebral cortex retina eye primary motor cortex frontal cortex forebrain spinal cord lumbar spinal cord lumbar spinal cord dorsal horn frontal lobe gray matter of forebrain lumbar spinal cord white matter lumbar spinal cord gray matter lumbar spinal cord ventral horn lumbar spinal cord lateral horn