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        <rdfs:comment>This cell type is compatible with the HIPC Lyoplate markers for &#39;naive B cell&#39;. Per DSD: Naive B cells are also reportedly CD10-negative, CD19-positive, CD20-positive, CD21-positive, CD22-positive, CD25-negative, CD27-negative, CD34-negative, CD40-positive, CD43-negative, CD45-positive, CD48-positive, CD53-positive, CD80-negative, CD81-positive, CD84-positive, CD86-negative, CD95-negative, CD138-negative, CD150-positive, CD184/CXCR4-positive, CD185/CXCR5-positive, CD196/CCR6-positive, CD200-positive, CD229-positive, CD243-positive, CD289-positive, CD290-positive, CD352-positive, MHCII/HLA-DR-positive, cadherin 9-positive, and sIgH-positive, Transcription factors: Pax5-positive, ETS1-positive, FOXO1A-positive, KLF4-positive, KLF9-positive, MiTF-positive, OBF1-positive, PLZF-positive, and SpiB-positive.</rdfs:comment>
        <ns5:ccf_pref_label>naive b cell</ns5:ccf_pref_label>
        <oboInOwl:hasExactSynonym>naive B-cell</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>naive B lymphocyte</oboInOwl:hasExactSynonym>
        <skos:prefLabel>Naive B Cell</skos:prefLabel>
        <oboInOwl:hasExactSynonym>naive B-lymphocyte</oboInOwl:hasExactSynonym>
        <skos:prefLabel>naive B cell</skos:prefLabel>
        <ns4:IAO_0000115>A naive B cell is a mature B cell that has the phenotype surface IgD-positive, surface IgM-positive, CD20-positive, CD27-negative and that has not yet been activated by antigen in the periphery.</ns4:IAO_0000115>
        <oboInOwl:id>CL:0000788</oboInOwl:id>
        <ns5:ccf_asctb_type>CT</ns5:ccf_asctb_type>
        <ns5:ccf_ct_isa rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
        <ns5:ccf_ct_isa rdf:resource="http://purl.obolibrary.org/obo/CL_0000945"/>
        <ns4:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000029"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000178"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001250"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001959"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002006"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002106"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002124"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002125"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002370"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002371"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004041"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004042"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0005483"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0009039"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0010395"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0010401"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0010420"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0010421"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0010753"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0013132"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_1000023"/>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas"/>
        <ns5:ccf_located_in rdf:resource="https://purl.org/ccf/ASCTB-TEMP_sheathed-capillary"/>
        <ns5:ccf_located_in rdf:resource="https://purl.org/ccf/ASCTB-TEMP_superficial-mantle-zone"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000945 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000945">
        <rdfs:label>lymphocyte of B lineage</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9606 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606">
        <rdfs:label>Homo sapiens</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/SO_0001260 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/SO_0001260">
        <rdfs:label>sequence collection</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000029 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000029">
        <rdfs:label>lymph node</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000178 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000178">
        <rdfs:label>blood</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0001250 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001250">
        <rdfs:label>red pulp of spleen</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0001959 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001959">
        <rdfs:label>white pulp of spleen</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0002006 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002006">
        <rdfs:label>cortex of lymph node</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0002106 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002106">
        <rdfs:label>spleen</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0002124 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002124">
        <rdfs:label>medulla of thymus</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0002125 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002125">
        <rdfs:label>thymus lobule</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0002370 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002370">
        <rdfs:label>thymus</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0002371 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002371">
        <rdfs:label>bone marrow</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0004041 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0004041">
        <rdfs:label>spleen primary B follicle</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0004042 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0004042">
        <rdfs:label>spleen secondary B follicle</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0005483 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0005483">
        <rdfs:label>thymus lobe</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0009039 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0009039">
        <rdfs:label>lymph node germinal center</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0010395 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0010395">
        <rdfs:label>lymph node primary follicle</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0010401 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0010401">
        <rdfs:label>spleen central arteriole</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0010420 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0010420">
        <rdfs:label>lymph node germinal center mantle zone</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0010421 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0010421">
        <rdfs:label>spleen B cell corona</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0010753 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0010753">
        <rdfs:label>lymph node secondary follicle</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0013132 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0013132">
        <rdfs:label>penicillar arteriole</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_1000023 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_1000023">
        <rdfs:label>spleen pulp</rdfs:label>
    </Class>
    


    <!-- https://purl.org/ccf/ASCTB-TEMP_sheathed-capillary -->

    <Class rdf:about="https://purl.org/ccf/ASCTB-TEMP_sheathed-capillary">
        <rdfs:label>sheathed capillary</rdfs:label>
    </Class>
    


    <!-- https://purl.org/ccf/ASCTB-TEMP_superficial-mantle-zone -->

    <Class rdf:about="https://purl.org/ccf/ASCTB-TEMP_superficial-mantle-zone">
        <rdfs:label>superficial mantle zone</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



