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    <!-- http://purl.obolibrary.org/obo/RO_0015004 -->

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        <rdfs:label>has characterizing marker set</rdfs:label>
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    <!-- http://purl.org/ccf/has_marker_component -->

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        <rdfs:label>has marker component</rdfs:label>
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    <!-- 
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    <!-- http://identifiers.org/hgnc/11922 -->

    <Class rdf:about="http://identifiers.org/hgnc/11922">
        <rdfs:label>CD27</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/13203 -->

    <Class rdf:about="http://identifiers.org/hgnc/13203">
        <rdfs:label>AICDA</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/1628 -->

    <Class rdf:about="http://identifiers.org/hgnc/1628">
        <rdfs:label>CD14</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/1633 -->

    <Class rdf:about="http://identifiers.org/hgnc/1633">
        <rdfs:label>CD19</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/29602 -->

    <Class rdf:about="http://identifiers.org/hgnc/29602">
        <rdfs:label>PDPN</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/4931 -->

    <Class rdf:about="http://identifiers.org/hgnc/4931">
        <rdfs:label>HLA-A</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/4932 -->

    <Class rdf:about="http://identifiers.org/hgnc/4932">
        <rdfs:label>HLA-B</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/4933 -->

    <Class rdf:about="http://identifiers.org/hgnc/4933">
        <rdfs:label>HLA-C</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/4947 -->

    <Class rdf:about="http://identifiers.org/hgnc/4947">
        <rdfs:label>HLA-DRA</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/5480 -->

    <Class rdf:about="http://identifiers.org/hgnc/5480">
        <rdfs:label>IGHD</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/5541 -->

    <Class rdf:about="http://identifiers.org/hgnc/5541">
        <rdfs:label>IGHM</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/7107 -->

    <Class rdf:about="http://identifiers.org/hgnc/7107">
        <rdfs:label>MKI67</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/7315 -->

    <Class rdf:about="http://identifiers.org/hgnc/7315">
        <rdfs:label>MS4A1</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/8760 -->

    <Class rdf:about="http://identifiers.org/hgnc/8760">
        <rdfs:label>PDCD1</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000000 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000000">
        <rdfs:label>cell</rdfs:label>
        <rdfs:label xml:lang="en">cell type (from CL)</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000785 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000785">
        <rdfs:label>mature B cell</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000844 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000844">
        <rdfs:label>germinal center B cell</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000785"/>
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            <Restriction>
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                        <intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/SO_0001260"/>
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                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
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                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
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                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/1628"/>
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                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/4947"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/5541"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
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                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/8760"/>
                            </Restriction>
                        </intersectionOf>
                    </Class>
                </someValuesFrom>
            </Restriction>
        </rdfs:subClassOf>
        <skos:prefLabel>Germinal Center B Cell</skos:prefLabel>
        <oboInOwl:hasExactSynonym>GC B cell</oboInOwl:hasExactSynonym>
        <ns4:IAO_0000115>A rapidly cycling mature B cell that has distinct phenotypic characteristics and is involved in T-dependent immune responses and located typically in the germinal centers of lymph nodes. This cell type expresses Ly77 after activation.</ns4:IAO_0000115>
        <oboInOwl:hasExactSynonym>germinal center B-lymphocyte</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>germinal center B-cell</oboInOwl:hasExactSynonym>
        <ns5:ccf_pref_label>germinal center b cell</ns5:ccf_pref_label>
        <oboInOwl:id>CL:0000844</oboInOwl:id>
        <oboInOwl:hasExactSynonym>GC B lymphocyte</oboInOwl:hasExactSynonym>
        <rdfs:comment>Germinal center B cells are also reportedly CD10-positive, CD19-positive, CD20-positive, CD38-positive, CD44-low, CD45-positive, CD48-positive, CD95-positive, CD352-positive, and HLA-DR-positive. Transcription factors: BCL6-positive, Ets1-positive, IRF8-positive, MTA3-positive, OBF1-positive, PAX5-positive, SpiB-positive, and STAT3-positive.</rdfs:comment>
        <oboInOwl:hasExactSynonym>germinal center B lymphocyte</oboInOwl:hasExactSynonym>
        <skos:prefLabel>germinal center B cell</skos:prefLabel>
        <oboInOwl:hasExactSynonym>GC B-cell</oboInOwl:hasExactSynonym>
        <ns5:ccf_asctb_type>CT</ns5:ccf_asctb_type>
        <oboInOwl:hasExactSynonym>GC B-lymphocyte</oboInOwl:hasExactSynonym>
        <ns5:ccf_ct_isa rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
        <ns4:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001959"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002106"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002373"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004042"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0005196"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0010754"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0013688"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_1000023"/>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas"/>
        <ns5:ccf_located_in rdf:resource="https://purl.org/ccf/ASCTB-TEMP_tonsil-follicle"/>
        <ns5:ccf_located_in rdf:resource="https://purl.org/ccf/ASCTB-TEMP_tonsil-secondary-follicle"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9606 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606">
        <rdfs:label>Homo sapiens</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/SO_0001260 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/SO_0001260">
        <rdfs:label>sequence collection</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0001959 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001959">
        <rdfs:label>white pulp of spleen</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0002106 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002106">
        <rdfs:label>spleen</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0002373 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002373">
        <rdfs:label>palatine tonsil</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0004042 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0004042">
        <rdfs:label>spleen secondary B follicle</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0005196 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0005196">
        <rdfs:label>spleen germinal center</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0010754 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0010754">
        <rdfs:label>germinal center</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0013688 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0013688">
        <rdfs:label>tonsil germinal center</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_1000023 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_1000023">
        <rdfs:label>spleen pulp</rdfs:label>
    </Class>
    


    <!-- https://purl.org/ccf/ASCTB-TEMP_tonsil-follicle -->

    <Class rdf:about="https://purl.org/ccf/ASCTB-TEMP_tonsil-follicle">
        <rdfs:label>tonsil follicle</rdfs:label>
    </Class>
    


    <!-- https://purl.org/ccf/ASCTB-TEMP_tonsil-secondary-follicle -->

    <Class rdf:about="https://purl.org/ccf/ASCTB-TEMP_tonsil-secondary-follicle">
        <rdfs:label>tonsil secondary follicle</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



