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     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:core="http://purl.obolibrary.org/obo/uberon/core#"
     xmlns:ns5="http://purl.org/ccf/"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:ccf="https://purl.org/ccf/"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:skos="http://www.w3.org/2004/02/skos/core#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
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    <AnnotationProperty rdf:about="http://purl.org/ccf/ccf_pref_label"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas">
        <rdfs:label>human_reference_atlas</rdfs:label>
    </AnnotationProperty>
    <AnnotationProperty rdf:about="http://purl.org/ccf/ccf_located_in"/>
    <AnnotationProperty rdf:about="http://www.w3.org/2004/02/skos/core#prefLabel"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasBroadSynonym"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.org/ccf/ccf_ct_isa"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="http://purl.org/ccf/ccf_asctb_type"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002175"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
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    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/RO_0015004 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0015004">
        <rdfs:label>has characterizing marker set</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.org/ccf/has_marker_component -->

    <ObjectProperty rdf:about="http://purl.org/ccf/has_marker_component">
        <rdfs:label>has marker component</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://identifiers.org/hgnc/10627 -->

    <Class rdf:about="http://identifiers.org/hgnc/10627">
        <rdfs:label>CCL3</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/10630 -->

    <Class rdf:about="http://identifiers.org/hgnc/10630">
        <rdfs:label>CCL4</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/12029 -->

    <Class rdf:about="http://identifiers.org/hgnc/12029">
        <rdfs:label>TRAC</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/1608 -->

    <Class rdf:about="http://identifiers.org/hgnc/1608">
        <rdfs:label>CCR7</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/1673 -->

    <Class rdf:about="http://identifiers.org/hgnc/1673">
        <rdfs:label>CD3D</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/1674 -->

    <Class rdf:about="http://identifiers.org/hgnc/1674">
        <rdfs:label>CD3E</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/1678 -->

    <Class rdf:about="http://identifiers.org/hgnc/1678">
        <rdfs:label>CD4</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/1706 -->

    <Class rdf:about="http://identifiers.org/hgnc/1706">
        <rdfs:label>CD8A</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/24961 -->

    <Class rdf:about="http://identifiers.org/hgnc/24961">
        <rdfs:label>HOPX</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/4709 -->

    <Class rdf:about="http://identifiers.org/hgnc/4709">
        <rdfs:label>GZMB</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/9666 -->

    <Class rdf:about="http://identifiers.org/hgnc/9666">
        <rdfs:label>PTPRC</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000000 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000000">
        <rdfs:label>cell</rdfs:label>
        <rdfs:label xml:lang="en">cell type (from CL)</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000084 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000084">
        <rdfs:label>T cell</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0001050 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0001050">
        <rdfs:label>effector CD8-positive, alpha-beta T cell</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0002419"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0015004"/>
                <someValuesFrom>
                    <Class>
                        <intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/SO_0001260"/>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/10627"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/10630"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/12029"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/1608"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/1673"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/1674"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/1678"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/1706"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/24961"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/4709"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/9666"/>
                            </Restriction>
                        </intersectionOf>
                    </Class>
                </someValuesFrom>
            </Restriction>
        </rdfs:subClassOf>
        <ns5:ccf_pref_label>cd8+ t cell</ns5:ccf_pref_label>
        <oboInOwl:id>CL:0001050</oboInOwl:id>
        <ns5:ccf_pref_label>cd8 t cell effector memory</ns5:ccf_pref_label>
        <oboInOwl:hasExactSynonym>effector CD8-positive, alpha-beta T-cell</oboInOwl:hasExactSynonym>
        <oboInOwl:hasBroadSynonym>effector CD8+ T cell</oboInOwl:hasBroadSynonym>
        <ns5:ccf_asctb_type>CT</ns5:ccf_asctb_type>
        <rdfs:comment>This cell type is compatible with the HIPC Lyoplate markers for &#39;effector CD8+ T cell&#39;.  The functional characteristics of this cell type currently undefined in CL, which affects its proper placement within the hierarchy.</rdfs:comment>
        <oboInOwl:hasExactSynonym>effector CD8-positive, alpha-beta T lymphocyte</oboInOwl:hasExactSynonym>
        <skos:prefLabel>CD8+ T Cell</skos:prefLabel>
        <skos:prefLabel>CD8 T cell effector memory</skos:prefLabel>
        <oboInOwl:hasExactSynonym>effector CD8-positive, alpha-beta T-lymphocyte</oboInOwl:hasExactSynonym>
        <ns4:IAO_0000115>A CD8-positive, alpha-beta T cell with the phenotype CCR7-negative, CD45RA-positive.</ns4:IAO_0000115>
        <ns5:ccf_ct_isa rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
        <ns5:ccf_ct_isa rdf:resource="http://purl.obolibrary.org/obo/CL_0000084"/>
        <ns4:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0000178"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001959"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001960"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002106"/>
        <ns5:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_1000023"/>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas"/>
        <ns5:ccf_located_in rdf:resource="https://purl.org/ccf/ASCTB-TEMP_inner-pals"/>
        <ns5:ccf_located_in rdf:resource="https://purl.org/ccf/ASCTB-TEMP_outer-pals"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0002419 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0002419">
        <rdfs:label>mature T cell</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9606 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606">
        <rdfs:label>Homo sapiens</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/SO_0001260 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/SO_0001260">
        <rdfs:label>sequence collection</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0000178 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000178">
        <rdfs:label>blood</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0001959 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001959">
        <rdfs:label>white pulp of spleen</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0001960 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001960">
        <rdfs:label>periarterial lymphatic sheath</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0002106 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002106">
        <rdfs:label>spleen</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_1000023 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_1000023">
        <rdfs:label>spleen pulp</rdfs:label>
    </Class>
    


    <!-- https://purl.org/ccf/ASCTB-TEMP_inner-pals -->

    <Class rdf:about="https://purl.org/ccf/ASCTB-TEMP_inner-pals">
        <rdfs:label>inner pals</rdfs:label>
    </Class>
    


    <!-- https://purl.org/ccf/ASCTB-TEMP_outer-pals -->

    <Class rdf:about="https://purl.org/ccf/ASCTB-TEMP_outer-pals">
        <rdfs:label>outer pals</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



