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     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:ns6="http://purl.org/ccf/"
     xmlns:ns5="http://purl.obolibrary.org/obo/"
     xmlns:core="http://purl.obolibrary.org/obo/uberon/core#"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:dcterms="http://purl.org/dc/terms/"
     xmlns:skos="http://www.w3.org/2004/02/skos/core#"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
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    //
    // Annotation properties
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    <AnnotationProperty rdf:about="http://purl.org/ccf/ccf_pref_label"/>
    <AnnotationProperty rdf:about="http://purl.org/dc/terms/contributor"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas">
        <rdfs:label>human_reference_atlas</rdfs:label>
    </AnnotationProperty>
    <AnnotationProperty rdf:about="http://purl.org/ccf/ccf_located_in"/>
    <AnnotationProperty rdf:about="http://www.w3.org/2004/02/skos/core#prefLabel"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.org/ccf/ccf_ct_isa"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#creation_date"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#inSubset"/>
    <AnnotationProperty rdf:about="http://purl.org/ccf/ccf_asctb_type"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002175"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
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    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
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    <!-- http://purl.obolibrary.org/obo/RO_0015004 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0015004">
        <rdfs:label>has characterizing marker set</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.org/ccf/has_marker_component -->

    <ObjectProperty rdf:about="http://purl.org/ccf/has_marker_component">
        <rdfs:label>has marker component</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://identifiers.org/hgnc/10494 -->

    <Class rdf:about="http://identifiers.org/hgnc/10494">
        <rdfs:label>S100A4</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/13177 -->

    <Class rdf:about="http://identifiers.org/hgnc/13177">
        <rdfs:label>IKZF2</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/1678 -->

    <Class rdf:about="http://identifiers.org/hgnc/1678">
        <rdfs:label>CD4</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/16830 -->

    <Class rdf:about="http://identifiers.org/hgnc/16830">
        <rdfs:label>IL32</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/2505 -->

    <Class rdf:about="http://identifiers.org/hgnc/2505">
        <rdfs:label>CTLA4</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/26838 -->

    <Class rdf:about="http://identifiers.org/hgnc/26838">
        <rdfs:label>TIGIT</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/33701 -->

    <Class rdf:about="http://identifiers.org/hgnc/33701">
        <rdfs:label>CARD16</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/4183 -->

    <Class rdf:about="http://identifiers.org/hgnc/4183">
        <rdfs:label>GBP2</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/6106 -->

    <Class rdf:about="http://identifiers.org/hgnc/6106">
        <rdfs:label>FOXP3</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/8987 -->

    <Class rdf:about="http://identifiers.org/hgnc/8987">
        <rdfs:label>PIM2</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/9108 -->

    <Class rdf:about="http://identifiers.org/hgnc/9108">
        <rdfs:label>PMAIP1</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/958 -->

    <Class rdf:about="http://identifiers.org/hgnc/958">
        <rdfs:label>BATF</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000000 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000000">
        <rdfs:label>cell</rdfs:label>
        <rdfs:label xml:lang="en">cell type (from CL)</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000624 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000624">
        <rdfs:label>CD4-positive, alpha-beta T cell</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0002677 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0002677">
        <rdfs:label>naive regulatory T cell</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000624"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0015004"/>
                <someValuesFrom>
                    <Class>
                        <intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/SO_0001260"/>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/10494"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/13177"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/1678"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/16830"/>
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                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/2505"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/26838"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/33701"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/4183"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/6106"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/8987"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/9108"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/958"/>
                            </Restriction>
                        </intersectionOf>
                    </Class>
                </someValuesFrom>
            </Restriction>
        </rdfs:subClassOf>
        <ns6:ccf_pref_label>regulatory t cells</ns6:ccf_pref_label>
        <rdfs:comment>This cell type has been described as CD45RA-negative, but this doesn&#39;t fit with our current definition of naive T cell.</rdfs:comment>
        <oboInOwl:hasExactSynonym>naive regulatory T-lymphocyte</oboInOwl:hasExactSynonym>
        <skos:prefLabel>regulatory T cells</skos:prefLabel>
        <oboInOwl:id>CL:0002677</oboInOwl:id>
        <oboInOwl:hasExactSynonym>naive regulatory T lymphocyte</oboInOwl:hasExactSynonym>
        <ns6:ccf_asctb_type>CT</ns6:ccf_asctb_type>
        <ns5:IAO_0000115>A regulatory T cell that has not encountered antigen.</ns5:IAO_0000115>
        <oboInOwl:hasExactSynonym>naive regulatory T-cell</oboInOwl:hasExactSynonym>
        <oboInOwl:creation_date>2011-08-25T03:17:21Z</oboInOwl:creation_date>
        <ns6:ccf_ct_isa rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
        <ns5:RO_0002175 rdf:resource="http://purl.obolibrary.org/obo/NCBITaxon_9606"/>
        <ns6:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002124"/>
        <ns6:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002125"/>
        <ns6:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0002370"/>
        <ns6:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0005483"/>
        <rdfs:isDefinedBy rdf:resource="http://purl.obolibrary.org/obo/cl.owl"/>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/uberon/core#human_reference_atlas"/>
        <dcterms:contributor rdf:resource="https://orcid.org/0000-0003-1980-3228"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9606 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606">
        <rdfs:label>Homo sapiens</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/SO_0001260 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/SO_0001260">
        <rdfs:label>sequence collection</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0002124 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002124">
        <rdfs:label>medulla of thymus</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0002125 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002125">
        <rdfs:label>thymus lobule</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0002370 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0002370">
        <rdfs:label>thymus</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0005483 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0005483">
        <rdfs:label>thymus lobe</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



