human_reference_atlas part of has characterizing marker set has marker component ROBO1 POSTN SYNPO2 PIEZO2 ITGA8 PDGFRB cell cell type (from CL) pericyte kidney corpuscule cell glomerular mesangial cell mesangial cell A mesangial cell located among the glomerular capillaries in a renal corpuscle. CL:1000742 Like smooth muscle, a glomerular mesangial cell is contractile and possesses the filaments actin and myosin. The contractile mechanism is also similar to that of smooth muscle, with Ca2+/calmodulin-activated myosin light-chain kinase instigating myosin-actin cross-bridge cycling. Mesangial cell phagocytosis of apoptotic neutrophils involves a novel CD36-independent, alpha(v)beta3/TSP-mediated mechanism that is uncoupled from chemokine secretion, emphasizing the injury-limiting potential of mesangial cell phagocytosis of apoptotic cells. CT Mesangial Cell KUPO:0001032 intraglomerular mesangial cell Homo sapiens sequence collection renal corpuscle nephron kidney mesangium glomerular mesangium kidney interstitium