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    <!-- http://purl.obolibrary.org/obo/NCBITaxon_9606 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/NCBITaxon_9606">
        <rdfs:label>Homo sapiens</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/UBERON_0000948 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0000948">
        <rdfs:label>heart</rdfs:label>
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        <foaf:depiction rdf:datatype="http://www.w3.org/2001/XMLSchema#anyURI">https://ccf-ontology.hubmapconsortium.org/objects/v1.2/VH_M_Heart.glb</foaf:depiction>
        <oboInOwl:id>UBERON:0000948</oboInOwl:id>
        <oboInOwl:hasDbXref>EHDAA:420</oboInOwl:hasDbXref>
        <ns4:UBPROP_0000003>As noted, the hearts of birds and mammals have four chambers that arises from the two chambers (atrium and ventricle) of the fish heart.[well established][VHOG]</ns4:UBPROP_0000003>
        <oboInOwl:hasDbXref>MA:0000072</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BILA:0000020</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>MIAA:0000036</oboInOwl:hasDbXref>
        <ns4:UBPROP_0000001>Part of the circulatory system responsible for pumping blood; composed of three chambers--two atria and one ventricle.[AAO]</ns4:UBPROP_0000001>
        <oboInOwl:hasDbXref>NCIT:C12727</oboInOwl:hasDbXref>
        <ns5:ccf_asctb_type>AS</ns5:ccf_asctb_type>
        <oboInOwl:hasDbXref>TAO:0000114</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>BTO:0000562</oboInOwl:hasDbXref>
        <ns4:UBPROP_0000002>relationship type change: differentiates_from lateral plate mesoderm (AAO:0010574) CHANGED TO: develops_from lateral plate mesoderm (UBERON:0003081)[AAO]</ns4:UBPROP_0000002>
        <ns5:ccf_pref_label>heart</ns5:ccf_pref_label>
        <oboInOwl:hasDbXref>MESH:D006321</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EFO:0000815</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>ZFA:0000114</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CALOHA:TS-0445</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>GAID:174</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>chambered heart</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>vertebrate heart</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>VHOG:0000276</oboInOwl:hasDbXref>
        <skos:prefLabel>heart</skos:prefLabel>
        <oboInOwl:hasDbXref>MAT:0000036</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>uberon</oboInOwl:hasOBONamespace>
        <oboInOwl:hasDbXref>EHDAA2:0000738</oboInOwl:hasDbXref>
        <ns4:IAO_0000115>A myogenic muscular circulatory organ found in the vertebrate cardiovascular system composed of chambers of cardiac muscle. It is the primary circulatory organ.</ns4:IAO_0000115>
        <oboInOwl:hasNarrowSynonym>branchial heart</oboInOwl:hasNarrowSynonym>
        <oboInOwl:hasDbXref>Wikipedia:Heart</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EV:0100018</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>galen:Heart</oboInOwl:hasDbXref>
        <rdfs:comment>Taxon notes:&quot; the ascidian tube-like heart lacks chambers....The ascidian heart is formed after metamorphosis as a simple tube-like structure with a single-layered myoepithelium that is continuous with a single-layered pericar- dial wall. It lacks chambers and endocardium.... The innovation of the chambered heart was a key event in vertebrate evolution, because the chambered heart generates one-way blood flow with high pressure, a critical requirement for the efficient blood supply of large-body vertebrates... all extant vertebrates have hearts with two or more chambers (Moorman and Christoffels 2003)&quot; DOI:10.1101/gad.1485706</rdfs:comment>
        <oboInOwl:hasDbXref>SCTID:302509004</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>EMAPA:16105</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>UMLS:C0018787</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>AAO:0010210</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>FMA:7088</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>XAO:0000064</oboInOwl:hasDbXref>
        <ns4:UBPROP_0000001>Blood pumping organ composed of four chambers: sinus venosus, atrium, cardiac ventricle and bulbus arteriosus.[TAO]</ns4:UBPROP_0000001>
        <oboInOwl:hasRelatedSynonym>cardium</oboInOwl:hasRelatedSynonym>
        <ns4:UBPROP_0000007>cardiac</ns4:UBPROP_0000007>
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        <ns5:ccf_part_of rdf:resource="http://purl.obolibrary.org/obo/UBERON_0013702"/>
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    <!-- http://purl.obolibrary.org/obo/UBERON_0003103 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0003103">
        <rdfs:label>compound organ</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/UBERON_0013702 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0013702">
        <rdfs:label>body proper</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0015410 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0015410">
        <rdfs:label>heart plus pericardium</rdfs:label>
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<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



