human_reference_atlas part of has part luminal cell of prostate epithelium basal cell of prostate epithelium Homo sapiens prostate epithelium prostate glandular acinus AS prostate glandular acinus prostatic follicle the muscle layer is implicitly treated as outside the acinus FMA:66808 uberon prostatic acinus UBERON:0004179 Prostate Glandular Acinus A saclike structure of the prostate gland, comprised of at least three cell layers: an innermost layer of secretory columnar luminal epithelium, a middle layer of squamous basal epithelium that also contains neuroendocrine cells, transit amplifying cells, and stem cells, and an outer layer of smooth muscle intermixed with other stromal cells. Concurrent with branching morphogenesis, the solid cords of epithelium formed by budding arborize and differentiate postnatally into glandular acin. The basic prostate architecture is established by puberty and acquires secretory function thereafter[PMID:18977204] multicellular anatomical structure