human_reference_atlas part of has characterizing marker set has marker component S100A8 S100A9 THBD CLEC7A CD14 CD163 CD19 CD1C CD36 CD3E CD53 CLEC10A CD74 CD86 CORO1A C1orf162 FCER1A FCER1G FCGR2B FCGR3A HLA-DRB1 IL3RA ITGAX NCAM1 SIRPA PTPRC cell cell type (from CL) myeloid dendritic cell dendritic cell, human CD1c-positive myeloid dendritic cell A myeloid dendritic cell found in the blood that is CD1c-positive. conventional dc 2 cdc2 cd1c-positive myeloid dendritic cell dendritic cell type 2 (DC2) dendritic cell type 3 (DC3) cDC2 CD1c-positive myeloid dendritic cell Conventional DC 2 conventional dendritic cell cdc2 cdc2 myeloid dendritic cell dendritic cell type 3 (dc3) dendritic cell type 2 (dc2) Normally represent 10-20% of peripheral blood mDCs (human). They are also CD281-positive (TLR1), CD282-positive (TLR2), CD283-positive (TLR3), CD284-positive (TLR4), CD285-positive (TLR5), CD286-positive (TLR6), CD288-positive (TLR8), and CD290-positive (TLR10) [PMID:20204387]. Upon TLR stimulation, these cells were potent producers of CXCL8 (IL-8), while producing little TNF-alpha. Conventional Dendritic Cell cDC2 CL:0002399 cDC2 myeloid dendritic cell CT 2010-10-04T02:39:01Z Homo sapiens sequence collection lymph node respiratory tract blood respiratory system lower respiratory tract white pulp of spleen periarterial lymphatic sheath cortex of lymph node lung spleen liver immune system liver lobule spleen perifollicular zone spleen pulp lymph node interfollicular cortex liver immune resident component red pulp-white pulp border