<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/CCFO?iri=http://purl.obolibrary.org/obo/CL_3000001"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:ns6="http://purl.org/ccf/"
     xmlns:ns5="http://purl.obolibrary.org/obo/"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:ccf="https://purl.org/ccf/"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:dcterms="http://purl.org/dc/terms/"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://purl.org/ccf/ccf_pref_label"/>
    <AnnotationProperty rdf:about="http://purl.org/dc/terms/contributor"/>
    <AnnotationProperty rdf:about="http://purl.org/ccf/ccf_ct_isa"/>
    <AnnotationProperty rdf:about="http://purl.org/ccf/ccf_located_in"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#creation_date"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasRelatedSynonym"/>
    <AnnotationProperty rdf:about="http://purl.org/ccf/ccf_asctb_type"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#id"/>
    


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    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
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    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
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     -->

    


    <!-- http://purl.obolibrary.org/obo/RO_0015004 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0015004">
        <rdfs:label>has characterizing marker set</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.org/ccf/has_marker_component -->

    <ObjectProperty rdf:about="http://purl.org/ccf/has_marker_component">
        <rdfs:label>has marker component</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://identifiers.org/hgnc/1631 -->

    <Class rdf:about="http://identifiers.org/hgnc/1631">
        <rdfs:label>CD163</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/1693 -->

    <Class rdf:about="http://identifiers.org/hgnc/1693">
        <rdfs:label>CD68</rdfs:label>
    </Class>
    


    <!-- http://identifiers.org/hgnc/3613 -->

    <Class rdf:about="http://identifiers.org/hgnc/3613">
        <rdfs:label>FCGR1A</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000000 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000000">
        <rdfs:label>cell</rdfs:label>
        <rdfs:label xml:lang="en">cell type (from CL)</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_0000864 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_0000864">
        <rdfs:label>tissue-resident macrophage</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CL_3000001 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CL_3000001">
        <rdfs:label>Hofbauer cell</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CL_0000864"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0015004"/>
                <someValuesFrom>
                    <Class>
                        <intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/SO_0001260"/>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/1631"/>
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                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/1693"/>
                            </Restriction>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.org/ccf/has_marker_component"/>
                                <someValuesFrom rdf:resource="http://identifiers.org/hgnc/3613"/>
                            </Restriction>
                        </intersectionOf>
                    </Class>
                </someValuesFrom>
            </Restriction>
        </rdfs:subClassOf>
        <oboInOwl:id>CL:3000001</oboInOwl:id>
        <oboInOwl:hasRelatedSynonym>HBC</oboInOwl:hasRelatedSynonym>
        <oboInOwl:creation_date>2019-02-18T19:41:20Z</oboInOwl:creation_date>
        <ns5:IAO_0000115>A tissue-resident macrophage that is part of the placenta. A Hofbauer cell expresses high levels of growth factors and metalloproteinases that support vasculogenesis, angiogenesis, branching morphogenesis and tissue remodeling. A Hofbauer cell has a fetal origin and is present throughout pregnancy.</ns5:IAO_0000115>
        <ns6:ccf_pref_label>hofbauer cell</ns6:ccf_pref_label>
        <rdfs:comment>Hofbauer cells are a heterogenic group of macrophages that resemble M2-like cells. Initially described in chorionic villi in humans, a Hofbauer cell is now often used to describe any fetal-derived placental macrophage that resides within the placental villous core, amnion, and chorion laeve.</rdfs:comment>
        <ns6:ccf_asctb_type>CT</ns6:ccf_asctb_type>
        <ns6:ccf_ct_isa rdf:resource="http://purl.obolibrary.org/obo/CL_0000000"/>
        <ns6:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0001987"/>
        <ns6:ccf_located_in rdf:resource="http://purl.obolibrary.org/obo/UBERON_0004027"/>
        <dcterms:contributor rdf:resource="https://orcid.org/0000-0001-6677-8489"/>
        <ns6:ccf_located_in rdf:resource="https://purl.org/ccf/ASCTB-TEMP_anchoring-villus"/>
        <ns6:ccf_located_in rdf:resource="https://purl.org/ccf/ASCTB-TEMP_floating-villus"/>
        <ns6:ccf_located_in rdf:resource="https://purl.org/ccf/ASCTB-TEMP_immature-intermediate-villus"/>
        <ns6:ccf_located_in rdf:resource="https://purl.org/ccf/ASCTB-TEMP_mature-intermediate-villus"/>
        <ns6:ccf_located_in rdf:resource="https://purl.org/ccf/ASCTB-TEMP_placental-disc"/>
        <ns6:ccf_located_in rdf:resource="https://purl.org/ccf/ASCTB-TEMP_stem-villus"/>
        <ns6:ccf_located_in rdf:resource="https://purl.org/ccf/ASCTB-TEMP_terminal-villus"/>
        <ns6:ccf_located_in rdf:resource="https://purl.org/ccf/ASCTB-TEMP_villous-mesenchyme"/>
        <dcterms:contributor rdf:resource="https://www.wikidata.org/entity/Q97529981"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/SO_0001260 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/SO_0001260">
        <rdfs:label>sequence collection</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0001987 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0001987">
        <rdfs:label>placenta</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/UBERON_0004027 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/UBERON_0004027">
        <rdfs:label>chorionic plate</rdfs:label>
    </Class>
    


    <!-- https://purl.org/ccf/ASCTB-TEMP_anchoring-villus -->

    <Class rdf:about="https://purl.org/ccf/ASCTB-TEMP_anchoring-villus">
        <rdfs:label>anchoring villus</rdfs:label>
    </Class>
    


    <!-- https://purl.org/ccf/ASCTB-TEMP_floating-villus -->

    <Class rdf:about="https://purl.org/ccf/ASCTB-TEMP_floating-villus">
        <rdfs:label>floating villus</rdfs:label>
    </Class>
    


    <!-- https://purl.org/ccf/ASCTB-TEMP_immature-intermediate-villus -->

    <Class rdf:about="https://purl.org/ccf/ASCTB-TEMP_immature-intermediate-villus">
        <rdfs:label>immature intermediate villus</rdfs:label>
    </Class>
    


    <!-- https://purl.org/ccf/ASCTB-TEMP_mature-intermediate-villus -->

    <Class rdf:about="https://purl.org/ccf/ASCTB-TEMP_mature-intermediate-villus">
        <rdfs:label>mature intermediate villus</rdfs:label>
    </Class>
    


    <!-- https://purl.org/ccf/ASCTB-TEMP_placental-disc -->

    <Class rdf:about="https://purl.org/ccf/ASCTB-TEMP_placental-disc">
        <rdfs:label>placental disc</rdfs:label>
    </Class>
    


    <!-- https://purl.org/ccf/ASCTB-TEMP_stem-villus -->

    <Class rdf:about="https://purl.org/ccf/ASCTB-TEMP_stem-villus">
        <rdfs:label>stem villus</rdfs:label>
    </Class>
    


    <!-- https://purl.org/ccf/ASCTB-TEMP_terminal-villus -->

    <Class rdf:about="https://purl.org/ccf/ASCTB-TEMP_terminal-villus">
        <rdfs:label>terminal villus</rdfs:label>
    </Class>
    


    <!-- https://purl.org/ccf/ASCTB-TEMP_villous-mesenchyme -->

    <Class rdf:about="https://purl.org/ccf/ASCTB-TEMP_villous-mesenchyme">
        <rdfs:label>villous mesenchyme</rdfs:label>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



