biological role ryanodine receptor modulator ryanodine receptor agonist RyR activator RyR activators A ryanodine receptor modulator which activates the receptor. Ryanodine receptors (RyRs) act as selective ion channels, modulating the release of calcium. Activating the receptors causes the release of calcium, so depleting internal calcium and ultimately preventing further muscle contraction. RyRs agonist CHEBI:67114 ryanodine receptor activators RyR agonist ryanodine receptor activator RyR agonists Wikipedia:Ryanodine_receptor RyRs activator chebi_ontology receptor activator activity