part_of has_part transcription regulatory region sequence-specific DNA binding nucleic acid binding transcription factor activity sequence-specific DNA binding transcription factor activity transcription factor activity Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex. molecular_function GO:0000130 GO:0003700 regulation of transcription, DNA-dependent