metallopeptidase activity Reactome:REACT_89528 Reactome:REACT_33929 Reactome:REACT_28662 Reactome:REACT_83988 Reactome:REACT_109532 Reactome:REACT_100129 Reactome:REACT_79691 Reactome:REACT_33366 Reactome:REACT_89928 Reactome:REACT_13658 Reactome:REACT_1552 Reactome:REACT_18387 metalloprotease activity Reactome:REACT_91564 Reactome:REACT_77236 Reactome:REACT_96651 Reactome:REACT_79817 Reactome:REACT_95565 Reactome:REACT_96136 Reactome:REACT_100372 Reactome:REACT_107504 Reactome:REACT_92210 Reactome:REACT_100694 Reactome:REACT_33539 Reactome:REACT_98562 Reactome:REACT_95173 Reactome:REACT_83198 Reactome:REACT_30292 Reactome:REACT_33852 Reactome:REACT_83310 Reactome:REACT_33732 Reactome:REACT_96860 Reactome:REACT_96983 Reactome:REACT_98127 Reactome:REACT_29018 Reactome:REACT_92309 Reactome:REACT_1011 Reactome:REACT_81981 Reactome:REACT_102999 GO:0008237 Reactome:REACT_410 Reactome:REACT_93042 Reactome:REACT_30924 Reactome:REACT_97764 Reactome:REACT_100593 Reactome:REACT_109423 Reactome:REACT_103085 Reactome:REACT_100677 Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions. Reactome:REACT_114094 metalloproteinase activity Reactome:REACT_99318 Reactome:REACT_115138 molecular_function Reactome:REACT_92841 Reactome:REACT_94705 Reactome:REACT_267 Reactome:REACT_104327 Reactome:REACT_101972 Reactome:REACT_78816 Reactome:REACT_104368 peptidase activity, acting on L-amino acid peptides