altered response to CNS ischemic injury decreased susceptibility to injury decreased susceptibility to ischemic brain injury MP:0006059 MPheno.ontology decreased susceptibility to spontaneous CNS ischemia increased resistance to ischemic brain injury less severe response, such as necrotic tissue size, to lack of adequate blood flow, due to trauma or disease, to support the normal functioning of all or part of the brain tissue, compared to controls reduced susceptibility to ischemic brain injury