abnormal ovarian follicle number abnormal primary ovarian follicle number abnormal numbers of the ovarian follicle prior to the appearance of an antrum, normally marked by developmental changes in the primary oocyte and follicular cells so that the latter form one or more layers of cuboidal or columnar cells; the follicle becomes surrounded by a sheath of stroma, the theca MPheno.ontology 2011-05-20T11:37:49Z MP:0011123 csmith