abnormal esophageal peristalsis abnormal gastroesophageal sphincter physiology esophageal achalasia 2012-01-18T10:35:52Z MP:0011570 MPheno.ontology achalasia of the cardia cardiospasm csmith failure of the normal relaxation of the lower esophageal sphincter associated with the uncoordinated contractions of the thoracic esophagus, resulting in functional obstruction