abnormal kidney physiology abnormal kidney epithelial cell primary cilium physiology abnormal renal epithelial cell primary cilium physiology 2012-09-27T04:19:00Z MP:0011744 MPheno.ontology abnormal kidney epithelial cell primary cilia physiology abnormal renal epithelial cell primary cilia physiology abnormal renal monocilium physiology abnormal renal primary cilium physiology any functional anomaly of the non-motile primary cilia found on renal epithelial cells and thought to act as a mechanical sensor to detect renal tubular fluid; impaired mechanical response of primary cilia to physiological fluid flow, or abnormalities in intracellular Ca2+ increase in response to fluid stress may alter renal (tubular) cell proliferation and differentiation and lead to renal cyst formation csmith abnormal nonmotile primary cilium physiology