abnormal neural crest cell morphology abnormal enteric neural crest cell morphology any structural anomaly of the neural crest cells that arise predominantly from the vagal region of the neural tube (vagal neural crest), adjacent to somites 1-7 and migrate rostro-caudally along the gastrointestinal tract to form two ganglionated plexuses of neurons and glial cells that comprise the enteric nervous system (ENS); a smaller proportion of ENCCs come from the sacral neural crest, caudal to somite 28, and migrate caudo-rostrally to colonize the distal gut; neural crest cells are termed enteric neural crest-derived cells upon entering the foregut at E9-9.5 in mice (after 4 weeks gestation in humans) 2014-05-06T00:00:00Z MP:0013001 MPheno.ontology abnormal ENCC morphology abnormal ENCDC morphology abnormal enteric neural crest-derived cell morphology csmith