polyacrylamide gel electrophoresis sodium dodecyl sulfate polyacrylamide gel electrophoresis CHMO:0001027 A separation method where colloidal particles move at different speeds according to their charge and frictional forces in a separation medium consisting of polyacrylamide gel, across which an electric field is applied, and the electrophoretic mobility of the analytes, usually proteins is altered by their binding to sodium dodecyl sulfate. sep:00173 SDS-PAGE SDS PAGE