two-dimensional liquid chromatography strong-cation-exchange reversed-phase high-performance liquid chromatography strong-cation-exchange reverse-phase HPLC https://orcid.org/0000-0001-5985-7429 A type of column chromatography where the mobile phase is a liquid, the stationary phase consists of very small particles and the inlet pressure is relatively high. An initial separation proceeds in a primary ion-exchange column (the particles of which shows no loss or gain of charge with varying pH) and parts of the eluent from this column are directed into a secondary column where the stationary phase is significantly less polar than the mobile phase. SCX-RP-HPLC 2009-06-19T11:05:17Z strong-cation-exchange reversed phase high-performance liquid chromatography strong cation exchange reverse phase high performance liquid chromatography strong-cation-exchang reversed-phase high-pressure liquid chromatography strong-cation-exchang reversed-phase HPLC CHMO:0001998 strong-cation-exchange reversed-phase high pressure liquid chromatography SCX-RP HPLC