Brain Diseases, Metabolic [Disease/Finding] Metabolism, Inborn Errors [Disease/Finding] Brain Diseases, Metabolic, Inborn [Disease/Finding] Brain disorders resulting from inborn metabolic errors, primarily from enzymatic defects which lead to substrate accumulation, product reduction, or increase in toxic metabolites through alternate pathways. The majority of these conditions are familial, however spontaneous mutation may also occur in utero. D020739 Brain Syndrome, Metabolic, Inborn M0328165 Encephalopathies, Metabolic, Inborn Inborn Metabolic Disorders, Brain Metabolic Brain Diseases, Inborn Inborn Errors of Metabolism, Brain Brain Diseases, Metabolic, Inborn Inborn Metabolic Brain Disorders Metabolic Brain Syndrome, Inborn Inborn Metabolic Brain Diseases 1022797 N0000004169 Metabolic Diseases, Inborn, Brain C0752109 Brain Diseases, Metabolic, Inborn C8516