chemical inhibits protein has role has role JQ1 PMID:27764802 PMID:27539364 InChI=1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m0/s1 0 PMID:28322577 PMID:27864418 PMID:28103888 (+)-JQ1 TEN-010 Wikipedia:JQ1 PMID:28275007 PDBeChem:JQ1 LINCS:LSM-6332 PMID:20871596 JQ1 PMID:28026145 PMID:26908627 PMID:23911322 (S)-(+)-tert-Butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-6-yl)acetate 456.990 PMID:26733615 C23H25ClN4O2S CAS:1268524-70-4 PMID:28368473 PMID:28254412 PMID:28143717 PMID:28490802 PMID:28467486 DNVXATUJJDPFDM-KRWDZBQOSA-N PMID:27443262 PMID:28118076 PMID:28504695 456.13867 tert-butyl [(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetate PMID:27528027 chebi_ontology Reference: PMID: 24391744 PMID:28105454 PMID:26830473 PMID:28484091 JQ1 Compound PMID:28515341 CHEBI:95080 (S)-JQ1 C(=O)(OC(C)(C)C)C[C@H]1C=2N(C3=C(C(=N1)C4=CC=C(C=C4)Cl)C(=C(S3)C)C)C(=NN2)C PMID:28270499 PMID:26791045 PMID:27117003 PMID:28134933 Reaxys:21994154 PMID:28418907 PMID:27573714 CHEBI:137113 PMID:27572308 A member of the class of thienotriazolodiazepines that is the tert-butyl ester of [(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetic acid. An inhibitor of bromodomain-containing protein 4 that exhibits anti-cancer and cardioprotective properties. PMID:28063381 PMID:27758824 PMID:28100400 PMID:26206333 PMID:28356707 PMID:28248992 PMID:27440272 PMID:28059436 PMID:27531767 PMID:27292261 PMID:28107481 bromodomain-containing protein 4 inhibitor tert-butyl ester carboxylic ester inhibitor antineoplastic agent organochlorine compound angiogenesis inhibitor anti-inflammatory agent apoptosis inducer cardioprotective agent thienotriazolodiazepine bromodomain-containing protein 2 bromodomain-containing protein 4