chemical modulates protein has role has role anticoronaviral agent PB28 PMID:23399765 Wikipedia:PB-28 370.581 PMID:28764962 PB 28 PMID:25637276 PMID:21744858 Chemspider:8649746 InChI=1S/C24H38N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h6,12,14,20-21H,2-5,7-11,13,15-19H2,1H3 370.29841 PMID:20021355 PMID:33052254 PMID:16687172 CAS:172906-90-0 PMID:16891467 PMID:29438891 PMID:31994091 PMID:19842660 PMID:15322732 PMID:21684636 Reference: PMID: 16891467 PHRCDWVPTULQMT-UHFFFAOYSA-N PB-28 A member of the class of tetralins that is tetralin that is substituted by 3-(4-cyclohexylpiperazin-1-yl)propyl and methoxy groups at positions 1 and 5, respectively. It is a sigma 2 (sigma2) receptor agonist (Ki = 0.68 nM) and exhibits antineoplastic and anti SARS-CoV-2 activities. CHEBI:189648 PMID:24697311 PMID:18178434 COC1=CC=CC2=C1CCCC2CCCN1CCN(CC1)C1CCCCC1 C24H38N2O chebi_ontology 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)-n-propyl]piperazine 1-cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine 1-cyclohexyl-4-[3-(1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl)propyl]piperazine PMID:34783163 PMID:21229979 PMID:22890883 PMID:20077462 PMID:33364961 0 PMID:19200007 1-(3-(5-methoxytetralin-1-yl)propyl)-4-cyclohexylpiperazine PMID:28086830 modulator sigma-2 receptor agonist piperazines antineoplastic agent aromatic ether tetralins apoptosis inducer sigma non-opioid intracellular receptor 1 sigma intracellular receptor 2