chemical inhibits protein has role has role XL413 Wikipedia:XL-413 PMID:29713760 PMID:26589264 PMID:34307771 CHEBI:189662 chebi_ontology BMS-863233 Chemspider:28508270 C14H12ClN3O2 PMID:32355159 PMID:30802412 [H][C@]1(CCCN1)C1=NC2=C(OC3=C2C=C(Cl)C=C3)C(=O)N1 BMS 863233 JJWLXRKVUJDJKG-VIFPVBQESA-N InChI=1S/C14H12ClN3O2/c15-7-3-4-10-8(6-7)11-12(20-10)14(19)18-13(17-11)9-2-1-5-16-9/h3-4,6,9,16H,1-2,5H2,(H,17,18,19)/t9-/m0/s1 XL-413 PMID:28560864 A benzofuropyrimidine that is 3,4-dihydro[1]benzofuro[3,2-d]pyrimidine substituted by (2S)-pyrrolidin-2-yl, oxo and chloro groups at positions 2, 4, and 8, respectively. It is a potent ATP competitive inhibitor of Cdc7 kinase (IC50 = 3.4 nM) and exhibits anticancer properties. DrugBank:DB12357 PMID:22560567 CAS:1169558-38-6 PMID:25412417 PMID:23064647 PDBeChem:0SX 289.720 Reference: PMID: 22560567 PMID:32521228 0 289.06180 8-chloro-2-[(2S)-pyrrolidin-2-yl][1]benzofuro[3,2-d]pyrimidin-4(3H)-one BMS863233 XL 413 benzofuropyrimidine inhibitor antineoplastic agent organochlorine compound pyrrolidines EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor DNA (cytosine-5)-methyltransferase 1