chemical inhibits protein has role has role ATPase motor cytoplasmic dynein inhibitor ferroptosis inhibitor bafilomycin A1 PMID:26242265 XDHNQDDQEHDUTM-JQWOJBOSSA-N InChI=1S/C35H58O9/c1-19(2)32-24(7)27(36)18-35(40,44-32)26(9)31(38)25(8)33-28(41-10)14-12-13-20(3)15-22(5)30(37)23(6)16-21(4)17-29(42-11)34(39)43-33/h12-14,16-17,19,22-28,30-33,36-38,40H,15,18H2,1-11H3/b14-12+,20-13+,21-16+,29-17-/t22-,23+,24-,25-,26-,27+,28-,30-,31+,32+,33+,35+/m0/s1 PMID:20820851 PMID:17917797 PMID:8446034 PMID:26156798 PMID:7817803 PMID:25512644 C35H58O9 PMID:22943412 PMID:19067440 PMID:23038011 0 622.40808 chebi_ontology Beilstein:4730699 The most used of the bafilomycins, a family of toxic macrolide antibiotics derived from Streptomyces griseus. PMID:23480984 Reference: PMID: 9572882 PMID:24977403 Beilstein:3640011 PMID:24890793 (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-16-{(2S,3R,4S)-4-[(2R,4R,5S,6R)-2,4-dihydroxy-6-isopropyl-5-methyltetrahydro-2H-pyran-2-yl]-3-hydroxypentan-2-yl}-8-hydroxy-3,15-dimethoxy-5,7,9,11-tetramethyloxacyclohexadeca-3,5,11,13-tetraen-2-one CO[C@H]1\C=C\C=C(C)\C[C@H](C)[C@H](O)[C@H](C)\C=C(C)\C=C(OC)\C(=O)O[C@@H]1[C@@H](C)[C@@H](O)[C@H](C)[C@@]1(O)C[C@@H](O)[C@H](C)[C@H](O1)C(C)C CAS:88899-55-2 622.82960 PMID:19289106 Beilstein:4730700 PMID:10519916 Reaxys:4730700 PMID:11533151 CHEBI:22689 PMID:22344969 fungicide macrolide antibiotic toxin oxanes EC 3.6.3.10 (H(+)/K(+)-exchanging ATPase) inhibitor cyclic hemiketal apoptosis inducer EC 3.6.3.14 (H(+)-transporting two-sector ATPase) inhibitor bacterial metabolite potassium ionophore autophagy inhibitor V-type proton ATPase subunit S1 V-type proton ATPase catalytic subunit A