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    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
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    <!-- http://purl.obolibrary.org/obo/RO_0000087 -->

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        <rdfs:label>has role</rdfs:label>
        <rdfs:label xml:lang="en">has role</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_22160 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_22160">
        <rdfs:label>acetamides</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_22315 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_22315">
        <rdfs:label>alkaloid</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_23359 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_23359">
        <rdfs:label>colchicine</rdfs:label>
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        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_22315"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35618"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_38032"/>
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            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_61951"/>
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                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_76924"/>
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        <oboInOwl:hasDbXref>LINCS:LSM-6449</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:10680067</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>DrugBank:DB01394</oboInOwl:hasDbXref>
        <ns5:inchikey>IAKHMKGGTNLKSZ-UHFFFAOYSA-N</ns5:inchikey>
        <ns3:IAO_0000115>An  alkaloid that is a carbotricyclic compound comprising 5,6,7,9-tetrahydrobenzo[a]heptalene having four methoxy substituents at the 1-, 2-, 3- and 10-positions as well as an oxo group at the 9-position and an acetamido group at the 7-position. It has been isolated from the plants belonging to genus Colchicum.</ns3:IAO_0000115>
        <ns5:smiles>COc1cc2CCC(NC(C)=O)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC</ns5:smiles>
        <ns5:formula>C22H25NO6</ns5:formula>
        <oboInOwl:hasDbXref>HMDB:HMDB0015466</oboInOwl:hasDbXref>
        <ns5:inchi>InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)</ns5:inchi>
        <oboInOwl:hasDbXref>PMID:7200520</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:24074178</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Beilstein:2228812</oboInOwl:hasDbXref>
        <ns5:monoisotopicmass>399.16819</ns5:monoisotopicmass>
        <oboInOwl:hasDbXref>Reaxys:2228812</oboInOwl:hasDbXref>
        <oboInOwl:id>CHEBI:23359</oboInOwl:id>
        <ns5:mass>399.43704</ns5:mass>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasDbXref>CAS:54192-66-4</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:9819133</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>N-(1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl)acetamide</oboInOwl:hasExactSynonym>
        <ns5:charge>0</ns5:charge>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_35618 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35618">
        <rdfs:label>aromatic ether</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_38032 -->

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        <rdfs:label>carbotricyclic compound</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_61951 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_61951">
        <rdfs:label>microtubule-destabilising agent</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_76924 -->

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        <rdfs:label>plant metabolite</rdfs:label>
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