has role has role desloratadine 310.82100 Patent:EP208855 Patent:US4659716 chebi_ontology LINCS:LSM-5887 Beilstein:4263164 PMID:11844681 DrugBank:DB00967 CAS:100643-71-8 DESLORATADINE 310.12368 Loratadine in which the ethoxycarbonyl group attached to the piperidine ring is replaced by hydrogen. The major metabolite of loratidine, desloratadine is an antihistamine which is used for the symptomatic relief of allergic conditions including rhinitis and chronic urticaria. It does not readily enter the central nervous system, so does not cause drowsiness. 8-chloro-11-(piperidin-4-ylidene)-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Drug_Central:814 C19H19ClN2 InChI=1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo(5,6)cyclohepta(1,2-b)pyridine Clc1ccc2c(CCc3cccnc3C2=C2CCNCC2)c1 PMID:15482930 8-Chloro-11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine descarboethoxyloratadine desloratadine PMID:9934454 CHEBI:291342 Wikipedia:Desloratadine 0 JAUOIFJMECXRGI-UHFFFAOYSA-N KEGG:D03693 H1-receptor antagonist benzocycloheptapyridine cholinergic antagonist drug metabolite anti-allergic agent