has part has part has_part chemical inhibits in vitro replication of virus has role has role radiosensitizing agent anticoronaviral agent gemcitabine gemcitabine hydrochloride CAS:122111-03-9 OKKDEIYWILRZIA-OSZBKLCCSA-N chebi_ontology 2'-deoxy-2',2'-difluorocytidine hydrochloride Beilstein:5386970 C9H12ClF2N3O4 KEGG:D01155 C9H11F2N3O4.HCl 0 InChI=1S/C9H11F2N3O4.ClH/c10-9(11)6(16)4(3-15)18-7(9)14-2-1-5(12)13-8(14)17;/h1-2,4,6-7,15-16H,3H2,(H2,12,13,17);1H/t4-,6-,7-;/m1./s1 2',2'-Difluorodeoxycytidine monohydrochloride DrugBank:DB00441 A 2'-deoxycytidine hydrochloriode having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine hydrochloride is used in the treatment of various carcinomas, including non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer. [H+].[Cl-].Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)C2(F)F)c(=O)n1 299.04844 CHEBI:31647 PMID: 24841273 299.65900 Gemcitabine HCl 2'-Deoxy-2',2'-difluorocytidine monohydrochloride antimetabolite antineoplastic agent immunosuppressive agent antiviral drug hydrochloride organofluorine compound EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor Middle East respiratory syndrome-related coronavirus Severe acute respiratory syndrome-related coronavirus