has role has role hexahydronaphthalenes polyketide carboxylic ester mevastatin KNApSAcK:C00000564 0 PMID:12403272 antibiotic ML 236B CS 500 mevastatinum CC[C@H](C)C(=O)O[C@H]1CCC=C2C=C[C@H](C)[C@H](CC[C@@H]3C[C@@H](O)CC(=O)O3)[C@@H]12 CAS:73573-88-3 Patent:US3983140 LINCS:LSM-4123 Reaxys:3630717 mevastatin Wikipedia:Mevastatin Patent:DE2524355 390.24062 PMID:18936176 chebi_ontology PMID:20629200 PMID:15274361 A carboxylic ester that is pravastatin that is lacking the allylic hydroxy group. A hydroxymethylglutaryl-CoA reductase inhibitor (statin) isolated from Penicillium citrinum and from Penicillium brevicompactum, its clinical use as a lipid-regulating drug ceased following reports of toxicity in animals. AJLFOPYRIVGYMJ-INTXDZFKSA-N PMID:15786722 PMID:24462564 mevastatin Mevastatin PMID:11283400 C23H34O5 PMID:15531285 390.51310 mevastatine KEGG:C13963 InChI=1S/C23H34O5/c1-4-14(2)23(26)28-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-18-12-17(24)13-21(25)27-18/h6,8-9,14-15,17-20,22,24H,4-5,7,10-13H2,1-3H3/t14-,15-,17+,18+,19-,20-,22-/m0/s1 mevastatina PMID:18672387 PMID:3719857 DrugBank:DB06693 ML-236B PMID:3170348 CHEBI:34848 (1S,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate ML 236 B PMID:23918904 Compactin antifungal agent apoptosis inducer 2-pyranones fungal metabolite Penicillium metabolite EC 3.4.24.83 (anthrax lethal factor endopeptidase) inhibitor statin (naturally occurring)