chemical binds protein has role has role protein binder clemastine Drug_Central:671 DrugBank:DB00283 clemastine Wikipedia:Clemastine clemastinum CHEBI:569763 clemastina 343.17029 CAS:15686-51-8 2-[(2R)-1-Methylpyrrolidin-2-yl]ethanol in which the hydrogen of the hydroxy group is substituted by a 1-(4-chlorophenyl)-1-phenylethyl group (R configuration). An antihistamine with antimuscarinic and moderate sedative properties, it is used as its fumarate salt for the symptomatic relief of allergic conditions such as rhinitis, urticaria, conjunctivitis and in pruritic (severe itching) skin conditions. C21H26ClNO 0 PMID:18788725 [H][C@@]1(CCCN1C)CCO[C@](C)(c1ccccc1)c1ccc(Cl)cc1 Reference: PMID: 22711801 InChI=1S/C21H26ClNO/c1-21(17-7-4-3-5-8-17,18-10-12-19(22)13-11-18)24-16-14-20-9-6-15-23(20)2/h3-5,7-8,10-13,20H,6,9,14-16H2,1-2H3/t20-,21-/m1/s1 (2R)-2-{2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl}-1-methylpyrrolidine 343.89000 KEGG:D03535 Patent:GB942152 KEGG:C06913 Beilstein:6486432 (+)-(2R)-2-[2-[[(R)-p-chloro-alpha-methyl-alpha-phenylbenzyl]oxy]ethyl]-1-methylpyrrolidine YNNUSGIPVFPVBX-NHCUHLMSSA-N CHEBI:3738 (+)-(2R)-2-(2-(((R)-p-chloro-alpha-methyl-alpha-phenylbenzyl)oxy)ethyl)-1-methylpyrrolidine Clemastine chebi_ontology LINCS:LSM-2655 H1-receptor antagonist N-alkylpyrrolidine muscarinic antagonist anti-allergic agent antipruritic drug monochlorobenzenes sigma non-opioid intracellular receptor 1 sigma intracellular receptor 2