is bearer of is_bearer_of chemical inhibits protein chemical has protein target as antagonist has role has role has functional parent is conjugate base of anticoronaviral agent antidepressant tricyclic antidepressant imipramine Clomipramine clomipramine Beilstein:1323477 314.15498 CiteXplore:16085036 chebi_ontology 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethyl-1-propanamine KEGG COMPOUND:C06918 C19H23ClN2 Drug_Central:701 CAS:303-49-1 PMID:19747949 InChI=1S/C19H23ClN2/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3 CN(C)CCCN1c2ccccc2CCc2ccc(Cl)cc12 2597 DrugBank:DB01242 chlorimipramine C19H23ClN2 Clomipramine CiteXplore:17471183 CiteXplore:19810911 https://www.drugbank.ca/drugs/DB01242 CiteXplore:12084414 CHEBI:3754 CN(C)CCCN1c2ccccc2CCc2ccc(Cl)cc12 Patent:US3467650 GDLIGKIOYRNHDA-UHFFFAOYSA-N ChemIDplus:303-49-1 CHEBI:47780 CiteXplore:12007764 Reaxys:1323477 ChemIDplus:1323477 monochlorimipramine G 34586 3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine 0 3-chloroimipramine PMID:12084414 Patent:CH371799 A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias. LINCS:LSM-3171 3-(3-CHLORO-5H-DIBENZO[B,F]AZEPIN-5-YL)-N,N-DIMETHYLPROPAN-1-AMINE KEGG:C06918 NIST Chemistry WebBook:303-49-1 PDBeChem:CXX 314.85210 KEGG COMPOUND:303-49-1 CHEBI:47359 PMID:12007764 PMID:16085036 InChI=1S/C19H23ClN2/c1-21(2)12-5-13-22-18-7-4-3-6-15(18)8-9-16-10-11-17(20)14-19(16)22/h3-4,6-7,10-11,14H,5,8-9,12-13H2,1-2H3 Wikipedia:Clomipramine InChIKey=GDLIGKIOYRNHDA-UHFFFAOYSA-N PMID:19810911 PMID:17471183 KEGG:D07727 dibenzoazepine serotonergic drug serotonergic antagonist serotonin uptake inhibitor clomipramine(1+) EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor function-inhibiting cytochrome P450 2D6 (CYP2D6) binding disposition cytochrome P450 isoenzyme 2C19 (CYP2C19) substrate disposition cytochrome P450 isoenzyme 2D6 (CYP2D6) substrate disposition glutathione S-transferase P (human) sodium-dependent noradrenaline transporter (human) 5-hydroxytryptamine receptor 2A (human) 5-hydroxytryptamine receptor 2C (human) sodium-dependent serotonin transporter (human) 5-hydroxytryptamine receptor 2B (human)