has role has role has functional parent has parent hydride is conjugate base of emetine(2+) emetic anticoronaviral agent antiamoebic agent antiviral agent isoquinoline alkaloid cephaeline antiinfective agent antineoplastic agent antiprotozoal drug emetan antimalarial emetine Emetine Beilstein:6253162 DrugBank:DB13393 Beilstein:100834 PMID:16109351 cephaline-O-methyl ether 0 methyl cephaeline PMID:14119536 KNApSAcK:C00001849 PMID:31775307 [H][C@]1(C[C@@]2([H])NCCc3cc(OC)c(OC)cc23)C[C@]2([H])N(CCc3cc(OC)c(OC)cc23)C[C@@H]1CC C29H40N2O4 6',7',10,11-tetramethoxyemetan Emetan PMID:31533472 Emetin MetaCyc:CPD-14817 480.29881 PMID:17094176 PMID:31436297 PMID:31964796 PMID:29872540 PMID:32251767 InChI=1S/C29H40N2O4/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24/h13-16,18,21,24-25,30H,6-12,17H2,1-5H3/t18-,21-,24+,25-/m0/s1 480.63898 cephaeline methyl ether PMID:19227966 PMID:32245264 Drug_Central:1001 chebi_ontology KEGG:C09421 Reaxys:100834 CAS:483-18-1 Wikipedia:Emetine LINCS:LSM-2041 AUVVAXYIELKVAI-CKBKHPSWSA-N CHEBI:4781 A pyridoisoquinoline comprising emetam having methoxy substituents at the 6'-, 7'-, 10- and 11-positions. It is an antiprotozoal agent and emetic. It inhibits SARS-CoV2, Zika and Ebola virus replication and displays antimalarial, antineoplastic and antiamoebic properties. PMID:31734270 protein synthesis inhibitor pyridoisoquinoline plant metabolite expectorant autophagy inhibitor