has part has part has_part chemical has protein target as agonist has role has role is conjugate base of donepezil (1+) EC 3.1.1.8 (cholinesterase) inhibitor EC 3.1.1.7 (acetylcholinesterase) inhibitor agonist donepezil 379.500 Reaxys:7081955 InChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3 Reference: PMID: 17328523 LINCS:LSM-1598 donepezilo KEGG:D07869 C24H29NO3 CAS:120014-06-4 ADEBPBSSDYVVLD-UHFFFAOYSA-N Wikipedia:Donepezil chebi_ontology DrugBank:DB00843 CHEBI:53289 donepezil C1(=C(C=C2C(=C1)CC(C2=O)(CC3CCN(CC3)CC4=CC=CC=C4)[H])OC)OC donepezilum 379.21474 Beilstein:7081955 Drug_Central:946 0 A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine. (S)-donepezil (R)-donepezil racemate nootropic agent sigma non-opioid intracellular receptor 1