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    <!-- http://purl.obolibrary.org/obo/CIDO_0000120 -->

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        <rdfs:label xml:lang="en">chemical has protein target as antagonist</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CIDO_0000121 -->

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        <rdfs:label xml:lang="en">chemical has protein target as agonist</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_26878 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_26878">
        <rdfs:label>tertiary alcohol</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_37143 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_37143">
        <rdfs:label>organofluorine compound</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_48279 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_48279">
        <rdfs:label>serotonergic antagonist</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_48561 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_48561">
        <rdfs:label>dopaminergic antagonist</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_48590 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_48590">
        <rdfs:label>hydroxypiperidine</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_48705 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_48705">
        <rdfs:label>agonist</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_48706 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_48706">
        <rdfs:label>antagonist</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_50919 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_50919">
        <rdfs:label>antiemetic</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_5613 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_5613">
        <rdfs:label>haloperidol</rdfs:label>
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        <oboInOwl:hasRelatedSynonym>gamma-(4-(p-chlorophenyl)-4-hydroxpiperidino)-p-fluorbutyrophenone</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:5613</oboInOwl:id>
        <ns5:charge>0</ns5:charge>
        <oboInOwl:hasRelatedSynonym>4-(4-(para-chlorophenyl)-4-hydroxypiperidino)-4&#39;-fluorobutyrophenone</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>Beilstein:331267</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:25007358</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:6725621</oboInOwl:hasDbXref>
        <ns5:monoisotopicmass>375.14013</ns5:monoisotopicmass>
        <oboInOwl:hasRelatedSynonym>4&#39;-fluoro-4-(4-hydroxy-4-(4&#39;-chlorophenyl)piperidino)butyrophenone</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Haldol</oboInOwl:hasRelatedSynonym>
        <ns3:IAO_0000119>Reference: PMID: 25592299</ns3:IAO_0000119>
        <ns5:formula>C21H23ClFNO2</ns5:formula>
        <oboInOwl:hasDbXref>LINCS:LSM-3512</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>4&#39;-fluoro-4-(4-(p-chlorophenyl)-4-hydroxypiperidinyl)butyrophenone</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>Wikipedia:Haloperidol</oboInOwl:hasDbXref>
        <ns5:inchikey>LNEPOXFFQSENCJ-UHFFFAOYSA-N</ns5:inchikey>
        <oboInOwl:hasDbXref>Reaxys:331267</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:C01814</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:7602118</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasDbXref>DrugBank:DB00502</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:D00136</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>haloperidolum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-one</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:11304647</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Patent:GB895309</oboInOwl:hasDbXref>
        <ns5:smiles>OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1</ns5:smiles>
        <oboInOwl:hasRelatedSynonym>1-(3-p-fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:10628896</oboInOwl:hasDbXref>
        <ns3:IAO_0000115>A compound composed of a central piperidine structure with hydroxy and p-chlorophenyl substituents at position 4 and an N-linked p-fluorobutyrophenone moiety.</ns3:IAO_0000115>
        <oboInOwl:hasExactSynonym>4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>Patent:US3438991</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>haloperidol</oboInOwl:hasRelatedSynonym>
        <ns5:inchi>InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2</ns5:inchi>
        <ns5:mass>375.86400</ns5:mass>
        <oboInOwl:hasDbXref>Patent:BE577977</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>CAS:52-86-8</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Drug_Central:1353</oboInOwl:hasDbXref>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <ns3:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_65190 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_65190">
        <rdfs:label>first generation antipsychotic</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_66956 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_66956">
        <rdfs:label>antidyskinesia agent</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_76224 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_76224">
        <rdfs:label>aromatic ketone</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_83403 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_83403">
        <rdfs:label>monochlorobenzenes</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/PR_000011650 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PR_000011650">
        <rdfs:label>sigma non-opioid intracellular receptor 1</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/PR_000032038 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PR_000032038">
        <rdfs:label>sigma intracellular receptor 2</rdfs:label>
    </Class>
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