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    <!-- http://purl.obolibrary.org/obo/CIDO_0000126 -->

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        <rdfs:label xml:lang="en">chemical activates protein</rdfs:label>
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        <rdfs:label>has role</rdfs:label>
        <rdfs:label xml:lang="en">has role</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_132922 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_132922">
        <rdfs:label>ibuprofen(1-)</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_176497 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_176497">
        <rdfs:label>geroprotector</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_25384 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_25384">
        <rdfs:label>monocarboxylic acid</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_30768 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_30768">
        <rdfs:label>propionic acid</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35475 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35475">
        <rdfs:label>non-steroidal anti-inflammatory drug</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35481 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35481">
        <rdfs:label>non-narcotic analgesic</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35493 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35493">
        <rdfs:label>antipyretic</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35703 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35703">
        <rdfs:label>xenobiotic</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_48578 -->

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        <rdfs:label>radical scavenger</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_50629 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_50629">
        <rdfs:label>cyclooxygenase 2 inhibitor</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_50630 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_50630">
        <rdfs:label>cyclooxygenase 1 inhibitor</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_5855 -->

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        <rdfs:label>ibuprofen</rdfs:label>
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        </rdfs:subClassOf>
        <oboInOwl:hasRelatedSynonym>(+-)-p-isobutylhydratropic acid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Seclodin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:14562167</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>4-isobutylhydratropic acid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Lebrufen</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>alpha-(4-isobutylphenyl)propionic acid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Anco</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:11433218</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>LINCS:LSM-1354</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>HMDB:HMDB0001925</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:24168233</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:15506544</oboInOwl:hasDbXref>
        <ns5:smiles>CC(C)Cc1ccc(cc1)C(C)C(O)=O</ns5:smiles>
        <oboInOwl:hasRelatedSynonym>Brufen</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Inoven</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Dolgit</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>(RS)-ibuprofen</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Dolgin</oboInOwl:hasRelatedSynonym>
        <ns3:IAO_0000115>A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(2-methylpropyl)phenyl group.</ns3:IAO_0000115>
        <oboInOwl:hasRelatedSynonym>Epobron</oboInOwl:hasRelatedSynonym>
        <ns5:charge>0</ns5:charge>
        <oboInOwl:hasRelatedSynonym>Advil</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Haltran</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Mynosedin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Nobgen</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Motrin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Trendar</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>2-(4-isobutylphenyl)propanoic acid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Lamidon</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>(+-)-2-(p-isobutylphenyl)propionic acid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Butylenin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>Wikipedia:Ibuprofen</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:D00126</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Adran</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>Patent:GB971700</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:25708941</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>alpha-(p-isobutylphenyl)propionic acid</oboInOwl:hasRelatedSynonym>
        <ns5:inchikey>HEFNNWSXXWATRW-UHFFFAOYSA-N</ns5:inchikey>
        <oboInOwl:hasDbXref>Reaxys:2049713</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Nuprin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>(4-isobutylphenyl)-alpha-methylacetic acid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:25915907</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>(+-)-ibuprofen</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>Patent:US6727286</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Pediaprofen</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Apsifen</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Ibutid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Anflagen</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Bluton</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Dolo-Dolgit</oboInOwl:hasRelatedSynonym>
        <ns5:mass>206.28082</ns5:mass>
        <oboInOwl:hasRelatedSynonym>Nurofen</oboInOwl:hasRelatedSynonym>
        <oboInOwl:id>CHEBI:5855</oboInOwl:id>
        <oboInOwl:hasDbXref>PMID:21368281</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Rufen</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>Drug_Central:1407</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Ebufac</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:18697608</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Beilstein:2049713</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>KEGG:C01588</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Patent:US5215755</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Ibuprofen</oboInOwl:hasExactSynonym>
        <oboInOwl:hasRelatedSynonym>Liptan</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:25521617</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:18335846</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>Patent:US3385886</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Inabrin</oboInOwl:hasRelatedSynonym>
        <ns5:inchi>InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)</ns5:inchi>
        <ns5:formula>C13H18O2</ns5:formula>
        <oboInOwl:hasRelatedSynonym>Buburone</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Femadon</oboInOwl:hasRelatedSynonym>
        <ns5:monoisotopicmass>206.13068</ns5:monoisotopicmass>
        <oboInOwl:hasRelatedSynonym>Tabalon</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Ibu-Attritin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Dolgirid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Medipren</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>(+-)-alpha-methyl-4-(2-methylpropyl)benzeneacetic acid</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>PMID:16176022</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Urem</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Brufort</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Suspren</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym>2-[4-(2-methylpropyl)phenyl]propanoic acid</oboInOwl:hasExactSynonym>
        <oboInOwl:hasRelatedSynonym>Ibuprocin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>CAS:15687-27-1</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>DrugBank:DB01050</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:29756342</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref>PMID:12723739</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym>Amibufen</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Ibumetin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym>Roidenin</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>Patent:US3228831</oboInOwl:hasDbXref>
        <oboInOwl:hasOBONamespace>chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasRelatedSynonym>Nobfen</oboInOwl:hasRelatedSynonym>
        <oboInOwl:inSubset rdf:resource="http://purl.oboInOwllibrary.org/oboInOwl/chebi#3_STAR"/>
        <ns3:IAO_0000412 rdf:resource="http://purl.obolibrary.org/obo/chebi.owl"/>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_78298 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_78298">
        <rdfs:label>environmental contaminant</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_88188 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_88188">
        <rdfs:label>drug allergen</rdfs:label>
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    <!-- http://purl.obolibrary.org/obo/PR_P37231 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/PR_P37231">
        <rdfs:label>peroxisome proliferator-activated receptor gamma (human)</rdfs:label>
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