chemical has protein target chemical inhibits protein chemical has protein target as antagonist chemical inhibits in vivo replication of virus chemical inhibits in vitro replication of virus has role has role has functional parent primary carboxamide anticoronaviral agent 1,2,4-triazole-3-carboxamide antiviral agent monocarboxylic acid amide antimetabolite inhibitor antiinfective agent carboxamide EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor aromatic amide ribavirin Ribavirin CiteXplore:22158703 A 1-ribosyltriazole that is the 1-ribofuranosyl derivative of 1,2,4-triazole-3-carboxamide. An inhibitor of HCV polymerase. ChemIDplus:36791-04-5 A 1-ribosyltriazole that is the 1-ribofuranosyl derivative of 1,2,4-triazole-3-carboxamide. A synthetic guanosine analogue, it is an inhibitor of HCV polymerase and possesses a broad spectrum of activity against DNA and RNA viruses. 0 ribavirin CiteXplore:22212566 https://www.drugbank.ca/drugs/DB00811 CiteXplore:22220723 CiteXplore:22052220 PMID:22156853 CiteXplore:22212569 CiteXplore:22212568 ChemIDplus:892462 1-beta-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide CiteXplore:22212572 CHEBI:63580 CiteXplore:22212576 PMID: 27344959; PMID: 26868298; PMID: 15200845; PMID: 16837072 CAS:36791-04-5 Drug_Central:2373 chebi_ontology LINCS:LSM-5701 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide InChI=1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1 PMID:29438107 Beilstein:892462 PMID:22220723 ribavirina PMID:21827730 CiteXplore:22239511 ribavirine DrugBank:DB00811 InChI=1S/C8H12N4O5/c9-6(16)7-10-2-12(11-7)8-5(15)4(14)3(1-13)17-8/h2-5,8,13-15H,1H2,(H2,9,16)/t3-,4-,5-,8-/m1/s1 244.08077 PMID:22052088 Wikipedia:Ribavirin Reaxys:892462 RBV PMID:22212568 InChIKey=IWUCXVSUMQZMFG-AFCXAGJDSA-N PMID:22212569 PMID:22212566 C8H12N4O5 NC(=O)c1ncn(n1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O CiteXplore:22156853 KEGG DRUG:36791-04-5 CiteXplore:21827730 PMID:22239511 CiteXplore:22239498 CHEBI:8840 C8H12N4O5 NC(=O)c1ncn(n1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O PMID:22158703 IWUCXVSUMQZMFG-AFCXAGJDSA-N PMID:22052220 CiteXplore:22212579 KEGG:D00423 244.20470 ribavirinum 1-beta-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide CiteXplore:22052088 9344 PMID:22212572 PMID: 24013700; PMID: 27344959 PMID:22239498 Reference: PMID: 22555152 PMID:22212579 KEGG DRUG:D00423 PMID:22212576 1-ribosyltriazole Middle East respiratory syndrome-related coronavirus Severe acute respiratory syndrome-related coronavirus inosine-5'-monophosphate dehydrogenase 2 inosine-5'-monophosphate dehydrogenase 2 (human) genome polyprotein (Dengue virus 2 Puerto Rico/PR159-S1/1969) inosine-5'-monophosphate dehydrogenase 1 (human) RNA-directed RNA polymerase L (HPIV-2) cytosolic purine 5'-nucleotidase (human)