is bearer of is_bearer_of chemical has protein target chemical inhibits protein chemical has protein target as agonist chemical effective in vitro against virus has role has role is conjugate base of anticoronaviral agent piperidines tertiary alcohol monocarboxylic acid amide mu-opioid receptor agonist antidiarrhoeal drug loperamide Loperamide ChemIDplus:53179-11-6 loperamidum KEGG COMPOUND:53179-11-6 PMID:15900907 InChIKey=RDOIQAHITMMDAJ-UHFFFAOYSA-N CN(C)C(=O)C(CCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1 PMID:24398461 476.22306 Beilstein:1558273 4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide InChI=1S/C29H33ClN2O2/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23/h3-16,34H,17-22H2,1-2H3 KEGG COMPOUND:C07080 HMDB:HMDB0004999 Patent:FR2100711 DrugBank:DB00836 Drug_Central:1599 CHEBI:6532 A synthetic piperidine derivative, effective against diarrhoea resulting from gastroenteritis or inflammatory bowel disease. 0 KEGG:D08144 Reaxys:1558273 C29H33ClN2O2 loperamide https://www.drugbank.ca/drugs/DB00836 chebi_ontology InChI=1S/C29H33ClN2O2/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23/h3-16,34H,17-22H2,1-2H3 477.03800 Patent:US3714159 Loperamide CN(C)C(=O)C(CCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1 LINCS:LSM-3365 KEGG:C07080 6468 loperamida loperamide Wikipedia:Loperamide CAS:53179-11-6 RDOIQAHITMMDAJ-UHFFFAOYSA-N PMID:19034106 PMID: 30918074; PMID: 27344959; PMID: 32366720 C29H33ClN2O2 monochlorobenzenes loperamide(1+) function-activating mu receptor binding disposition function-activating mu receptor binding disposition Middle East respiratory syndrome-related coronavirus Severe acute respiratory syndrome-related coronavirus voltage-dependent P/Q-type calcium channel subunit alpha-1A (human) pro-opiomelanocortin (human) calmodulin-1 (human) mu-type opioid receptor (human) delta-type opioid receptor (human) kappa-type opioid receptor (human)