chemical has protein target as antagonist has role has role has functional parent tertiary carboxamide geroprotector ethyl ester desloratadine organochlorine compound H1-receptor antagonist N-acylpiperidine benzocycloheptapyridine antagonist cholinergic antagonist anti-allergic agent loratadine Claritin 382.890 Chemspider:3820 Allerclear PMID:33550204 CHEBI:94763 loratadinum 0 Lorastine CHEBI:6538 CCOC(=O)N1CCC(CC1)=C1C2=C(CCC3=C1N=CC=C3)C=C(Cl)C=C2 Alerpriv PMID:32312261 Loradex loratadine C22H23ClN2O2 PMID:32694422 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester HMDB:HMDB0005000 PMID:7522069 loratadina Loradamed Civeran PMID:34121623 Claratyne PMID:34306392 Reference: PMID: 25318072 382.14481 LINCS:LSM-5891 Reaxys:4273483 Loracert Loratyne PMID:24134630 Aerotina JCCNYMKQOSZNPW-UHFFFAOYSA-N Wal-itin DrugBank:DB00455 ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate FooDB:FDB023577 CAS:79794-75-5 PMID:31315424 PMID:33673552 chebi_ontology PMID:31576110 KEGG:D00364 PMID:15627436 Alavert Wikipedia:Loratadine PMID:32877950 PMID:33963858 Alarin InChI=1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3 Drug_Central:1605 A benzocycloheptapyridine that is 6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine substituted by a chloro group at position 8 and a 1-(ethoxycarbonyl)piperidin-4-ylidene group at position 11. It is a H1-receptor antagonist commonly employed in the treatment of allergic disorders. sodium-dependent neutral amino acid transporter B(0)AT2