chemical has protein target as antagonist chemical inhibits in vitro replication of virus has role has role has functional parent anticoronaviral agent tertiary alcohol cephalotaxine antineoplastic agent organic heteropentacyclic compound alkaloid ester enol ether protein synthesis inhibitor apoptosis inducer omacetaxine mepesuccinate 0 KEGG:D08956 A cephalotaxine-derived alkaloid ester obtained from Cephalotaxus harringtonia; used for the treatment of chronic or accelerated phase chronic myeloid leukaemia. omacetaxine mepesuccinate PMID:22391162 PMID:21415308 PMID:22896000 PDBeChem:HMT PMID:21468038 PMID:22967374 PMID:22898909 545.26248 PMID:23109844 PMID:22289991 PMID:22075327 CHEBI:71019 545.62130 omacetaxini mepesuccinas C29H39NO9 CAS:26833-87-4 PMID:23086639 PMID:20971952 PMID:22917222 CGX-635 PMID:21509439 PMID:22580751 InChI=1S/C29H39NO9/c1-27(2,33)8-5-10-29(34,16-23(31)36-4)26(32)39-25-22(35-3)15-28-9-6-11-30(28)12-7-18-13-20-21(38-17-37-20)14-19(18)24(25)28/h13-15,24-25,33-34H,5-12,16-17H2,1-4H3/t24-,25-,28+,29-/m1/s1 Homoharringtonine mepesuccinato de omacetaxina HYFHYPWGAURHIV-JFIAXGOJSA-N PMID:21845438 (2'R,3S,4S,5R)-(-)-homoharringtonine Patent:WO2007089878 Drug_Central:4677 chebi_ontology [H][C@@]12[C@H](OC(=O)[C@@](O)(CCCC(C)(C)O)CC(=O)OC)C(OC)=C[C@@]11CCCN1CCc1cc3OCOc3cc21 PMID:21258877 PMID: 24841273 Wikipedia:Omacetaxine_mepesuccinate PMID:23053254 Patent:US2010240887 LINCS:LSM-3716 Reaxys:5687925 Synribo https://www.drugbank.ca/drugs/DB04865 Beilstein:5687925 mepesuccinate d'omacetaxine PMID:21916787 PMID:21294709 (-)-homoharringtonine PMID:21152934 PMID:23059828 PMID:22040954 PMID:22714632 PMID:22054289 PMID:21418889 PMID:23456623 Middle East respiratory syndrome-related coronavirus Severe acute respiratory syndrome-related coronavirus 60S ribosomal protein L3 (human)